Active pharmaceutical ingredients (APIs)
Here you will find selected examples of compounds, for which the production at ChemCon is already established or under development.
ChemCon’s APIs are released to current monographs or to defined specifications following validated internal methods. Please let us know which release specifications you require, and we will adjust our protocol accordingly.
Acetylcholine chloride [60-31-1]
CAS Number: 60-31-1
Molecular weight: 181.66 g/mol
Chemical formula: C7H16ClNO2
Synonyms: 2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride
(2-Acetoxyethyl)trimethylammonium chloride
Quality: GMP, injectable / ophthalmic grade
Development stage: validated
Alosetron Hydrochloride
CAS Number: 122852-69-1
Molecular weight: 330.81 g/mol
Chemical formula: C17H19ClN4O · HCl
Synonyme: 5-Methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-3,4-dihydro-2H-pyrido[4,3-b]indol-1(5H) hydrochloride
1H-Pyrido(4,3-b)indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-, monohydrochloride
2,3,4,5-Tetrahydro-5-methyl-2-((5-methylimidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one monohydrochloride
Quality: GMP
Development stage: intermediate, please contact us regarding timelines
Anagrelide
CAS Number: 823178-43-4
Molecular weight: 310.57 g/mol
Chemical formula: C10H7Cl2N3O · HCl · H2O
Quality: GMP, oral grade
Development stage: validated
Arsenic trioxide
CAS Number: 1327-53-3
Molecular weight: 197.84 g/mol
Chemical formula: As2O3
Synonyme: Arsenic(III)-oxide
Arsenous acid anhydride
Quality: GMP, injectable / oral grade
Development stage: validated
Chromium(III) chloride
CAS Number: 10060-12-5
Molecular weight: 266.41 g/mol
Chemical formula: CrCl3 · 6 H2O
Synonyms: chromium trichloride,
chromium chloride
Quality: GMP, injectable grade
Development stage: validated
Copper(II) chloride
CAS Number: 10125-13-0
Molecular weight: 170.48 g/mol
Chemical formula: CuCl2 · 2 H2O
Synonyms: copper dichloride, copper chloride
Quality: GMP, injectable grade
Development stage: validated
Copper tetraMIBI tetrafluoroborate
CAS Number: 103694-84-4
Molecular weight: 602.98 g/mol
Chemical formula:C24H44CuN4O4 ⋅ BF4
Synonyme: (2-Methoxy-2-methylpropaneisocyanide)copper(I) tetrafluoroborate
MIBI copper complex
Tetrakis(2-methoxyisobutyl isonitrile)copper(I) tetrafluoroborate
Quality: GMP, for the preparation of technetium sestaMIBI
Development stage: intermediate, please contact us regarding timelines
![[Translate to Englisch:] Structural formula copper tetraMIBI fluoroborate](/fileadmin/_processed_/6/c/csm_CuMIBI_839b75666d.jpg "[Translate to Englisch:] ChemCon copper tetraMIBI fluoroborate")
Curcumin
CAS Number: 458-37-7
Molecular weight: 368.39 g/mol
Chemical formula: C21H20O6
Synonyms:1,5-Divanillyliden-2,4-pentandione
1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
Curcumin
Diferuloylmethane
Development stage: early, please contact us regarding timelines
Fenoldopam
CAS Number: 54527-84-3
Molecular weight: 515.99 g/mol
Chemical formula: C16H16ClNO3
Synonyms: 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Quality: GMP, injectable grade
Development stage: validated
Histamine
CAS Number: 56-92-8
Molecular weight: 184.07 g/mol
Chemical formula: C5H9N3 · 2 HCl
Synonyms: 2-(1H-Imidazol-4-yl)ethanamine dihydrochloride
4-(2-Aminoethyl)imidazole dihydrochloride
Quality: GMP, topic grade
Development stage: validated
Validation of further release methods for oral / injectable grade is possible upon request.
Ibandronate
CAS Number: 138844-81-2
Molecular weight: 341,21 g/mol
Chemical formula: C9H22NaNO7P2
Synonyms:Phosphonic acid, (1-hydroxy-3-(methylpentylamino)propylidene)bis-, monosodium salt
Quality: GMP
Development stage: early, please contact us regarding timelines
Iron(III) chloride
CAS Number: 10025-77-1
Molecular weight: 270.30 g/mol
Chemical formula: FeCl3 · 6 H2O
Synonyms: iron trichloride, Ferric Chloride
Quality: GMP, injectable grade
Development stage: validated
Ketotifen
CAS Number: 34580-14-8
Molecular weight: 425.50 g/mol
Chemical formula: C19H19NOS · C4H4O4
Synonyms: 4,9-Dihydro-4-(1-methyl-4-piperidinylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophen-10-one
Quality: GMP, ophthalmic grade
Development stage: early, please contact us regarding timelines
L-Dopa ethyl ester (Etilevodopa) [37178-37-3]
CAS Number: 37178-37-3
Molecular weight: 224.24 g/mol
Chemical formula: C11H15NO4
Synonyms: (-)-3-(3,4-Dihydroxyphenyl)-L-alaninethylester
2-Amino-3-(3,4-dihydroxyphenyl)propansäurethylester
Levodopa ethyl ester
Etilevodopa
Quality: GMP, oral grade
Development stage: intermediate, please contact us regarding timelines
Validation of further release methods for injectable grade is possible upon request.
Malathion
CAS Number: 121-75-5
Molecular weight: 330.36 g/mol
Chemical formula: C10H19O6PS2
Synonyms: O,O-Dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl) dithiophosphate,
Butanedioic acid, ((dimethoxyphosphinothioyl)thio)-, diethyl ester
Quality: GMP, topic grade
Development stage: validated
Manganese(II) chloride
CAS Number: 13446-34-9
Molecular weight: 197.91 g/mol
Chemical formula: MnCl2 · 4 H2O
Synonyms: Manganese(II) chloride
Manganese dichloride
Quality: GMP, injectable grade
Development stage: validated
Manganese(II) sulfate monohydrate
CAS Number: 10034-96-5
Molecular weight: 169.02 g/mol
Chemical formula: MnSO4 ∙ H2O
Synonyms: -
Quality: GMP, injectable grade
Development stage: intermediate, please contact us regarding timelines
Melphalan free base
CAS Number: 148-82-3
Molecular weight: 305.199 g/mol
Chemical formula: C13H18Cl2N2O2
Synonyms: 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine,
3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine,
4-(Bis(2-chloroethyl)amino)-L-phenylalanine,
p-Di-(2-chloroethyl)amino-L-phenylalanine,
L-Sarcolysin
Quality: GMP, oral grade
Development stage: validated
Melphalan hydrochloride
CAS Number: 3223-07-2
Molecular weight: 341.66 g/mol
Chemical formula: C13H18Cl2N2O2 · HCl
Synonyms: 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine hydrochloride,
3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine hydrochloride,
4-(Bis(2-chloroethyl)amino)-L-phenylalanine hydrochloride,
p-Di-(2-chloroethyl)amino-L-phenylalanine hydrochloride,
L-Phenylalanine mustard hydrochloride
Quality: GMP, injectable grade
Development stage: validated
Metaarsenite sodium
CAS Number: 7784-46-5
Molecular weight: 129.92 g/mol
Chemical formula: NaAsO2
Synonyms: Sodium arsenite
Sodium arsenate(III)
Quality: GMP, oral grade
Development stage: intermediate, please contact us regarding timelines
Metadoxine
CAS-Number:74536-44-0
Molecular weight: 298.29 g/mol
Chemical formula: C13H18N2O6
Synonyms: 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol;(2S)-5-oxopyrrolidine-2-carboxylic acid
Quality: GMP oral grade
Development stage: advanced, please contact us regarding timelines
Methylene blue
CAS Number: 61-73-4
Molecular weight: 319.9 g/mol
Chemical formula: C16H18CIN3S
Synonyms: N,N,N′,N′-Tetramethylthioninchloride
3,7-Bis(dimethylamino)phenazathionium chloride
Methylthionium chloride
C.I. Basic Blue 9
Quality: GMP, injectable / oral grade
Development stage: advanced, please contact us regarding timelines
Sodium molybdate
CAS Number: 10102-40-6
Molecular weight: 241.95g/mol
Chemical formula: Na2MoO4 ∙ 2 H2O
Synonyms: Sodium molybdate dihydrate
Quality: GMP, injectable grade
Development stage: validated
Nicardipine
CAS Number: 54527-84-3
Molecular weight: 515.99 g/mol
Synonyms: 2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridine-3,5-dicarboxylat,
3,5-Pyridinedicarboxylic acid 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(benzylmethylamino)ethyl methyl ester
Chemical formula: C26H29N3O6 · HCl
Quality: GMP, injectable grade
Development stage: validated
Nitroprusside sodium
CAS Number: 13755-38-9
Molecular weight: 297.95 g/mol
Chemical formula: Na2[Fe(CN)5NO] · 2 H2O
Synonyms: Sodium nitroprusside,
Nitroprusside sodium,
Sodiumpentacyanidonitrosylferrat(II)-dihydrate,
Sodiumpentacyanonitrosylferrat(II)-dihydrate
Quality: GMP, injectable grade
Development stage: advanced, please contact us regarding timelines
Potassium Tetrabromoaurate (III)
CAS Number: 14323-32-1
Molecular weight: 555.68 g/mol
Chemical formula: KAuBr4 · H2O
Quality: GMP, injectable grade
Development stage: early, please contact us regarding timelines
Selenious acid
CAS Number: 7783-00-8
Molecular weight: 128.97 g/mol
Chemical formula: H2SeO3
Synonyms: Selenous acid, Selenic (IV) acid
Quality: GMP, injectable grade
Development stage: intermediate, please contact us regarding timelines
Sodium selenite
CAS Number: 10102-18-8
Molecular weight: 172.94g/mol
Chemical formula: Na2SeO3
Quality: GMP, injectable grade
Development stage: validated
Tetradecylsulfate sodium (STS / STDS)
CAS Number: 139-88-8
Molecular weight: 316.43 g/mol
Chemical formula: C14H29NaO4S
Synonyms: 7-Ethyl-2-methyl-4-hendecanol sulfate sodium salt,
Sodium 7-ethyl-2-methylundecyl-4-sulfate,
Sodium 2-methyl-7-ethylundecanol-4-sulfate
Quality: GMP, injectable grade
Development stage: validated
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